Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice

Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice

ABSTRACT The gut microbiome is linked to inflammatory bowel disease (IBD) severity and altered in late-stage disease. However, it is unclear how gut microbial communities change over the course of IBD development, especially in regard to function. To investigate microbiome-mediated disease mechanism...

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Bibliographic Details
Main Authors: Thomas Sharpton, Svetlana Lyalina, Julie Luong, Joey Pham, Emily M. Deal, Courtney Armour, Christopher Gaulke, Shomyseh Sanjabi, Katherine S. Pollard
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
inflammatory bowel disease
lipooligosaccharide transporter
longitudinal
metagenomics
protein function
statistics
Microbiology
QR1-502
Online Access:https://doaj.org/article/2dc46ba55ca047c98562fdedba938cd8
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https://doaj.org/article/2dc46ba55ca047c98562fdedba938cd8

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