A universal mechanism ties genotype to phenotype in trinucleotide diseases.

Trinucleotide hereditary diseases such as Huntington disease and Friedreich ataxia are cureless diseases associated with inheriting an abnormally large number of DNA trinucleotide repeats in a gene. The genes associated with different diseases are unrelated and harbor a trinucleotide repeat in diffe...

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Auteurs principaux: Shai Kaplan, Shalev Itzkovitz, Ehud Shapiro
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2007
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Accès en ligne:https://doaj.org/article/2dd5700087dc47ba8d533e8291fe36c7
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