Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes

Wnts are important for synapse formation and maintenance. Here, the authors show that proline-rich 7 (PRR7) is a Wnt inhibitor that is secreted via exosomes to regulate excitatory synapse numbers.

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Autores principales: Sang H. Lee, Seung Min Shin, Peng Zhong, Hyun-Taek Kim, Dong-Il Kim, June Myoung Kim, Won Do Heo, Dae-Won Kim, Chang-Yeol Yeo, Cheol-Hee Kim, Qing-song Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2dee18b6e6df45e992bdfb6659b177d0
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