Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes

Wnts are important for synapse formation and maintenance. Here, the authors show that proline-rich 7 (PRR7) is a Wnt inhibitor that is secreted via exosomes to regulate excitatory synapse numbers.

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Autores principales:	Sang H. Lee, Seung Min Shin, Peng Zhong, Hyun-Taek Kim, Dong-Il Kim, June Myoung Kim, Won Do Heo, Dae-Won Kim, Chang-Yeol Yeo, Cheol-Hee Kim, Qing-song Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2dee18b6e6df45e992bdfb6659b177d0
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spelling	oai:doaj.org-article:2dee18b6e6df45e992bdfb6659b177d02021-12-02T14:38:49ZReciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes10.1038/s41467-018-05858-22041-1723https://doaj.org/article/2dee18b6e6df45e992bdfb6659b177d02018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05858-2https://doaj.org/toc/2041-1723Wnts are important for synapse formation and maintenance. Here, the authors show that proline-rich 7 (PRR7) is a Wnt inhibitor that is secreted via exosomes to regulate excitatory synapse numbers.Sang H. LeeSeung Min ShinPeng ZhongHyun-Taek KimDong-Il KimJune Myoung KimWon Do HeoDae-Won KimChang-Yeol YeoCheol-Hee KimQing-song LiuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sang H. Lee Seung Min Shin Peng Zhong Hyun-Taek Kim Dong-Il Kim June Myoung Kim Won Do Heo Dae-Won Kim Chang-Yeol Yeo Cheol-Hee Kim Qing-song Liu Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
description	Wnts are important for synapse formation and maintenance. Here, the authors show that proline-rich 7 (PRR7) is a Wnt inhibitor that is secreted via exosomes to regulate excitatory synapse numbers.
format	article
author	Sang H. Lee Seung Min Shin Peng Zhong Hyun-Taek Kim Dong-Il Kim June Myoung Kim Won Do Heo Dae-Won Kim Chang-Yeol Yeo Cheol-Hee Kim Qing-song Liu
author_facet	Sang H. Lee Seung Min Shin Peng Zhong Hyun-Taek Kim Dong-Il Kim June Myoung Kim Won Do Heo Dae-Won Kim Chang-Yeol Yeo Cheol-Hee Kim Qing-song Liu
author_sort	Sang H. Lee
title	Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
title_short	Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
title_full	Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
title_fullStr	Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
title_full_unstemmed	Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
title_sort	reciprocal control of excitatory synapse numbers by wnt and wnt inhibitor prr7 secreted on exosomes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2dee18b6e6df45e992bdfb6659b177d0
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Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes

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