Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
Wnts are important for synapse formation and maintenance. Here, the authors show that proline-rich 7 (PRR7) is a Wnt inhibitor that is secreted via exosomes to regulate excitatory synapse numbers.
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Auteurs principaux: | Sang H. Lee, Seung Min Shin, Peng Zhong, Hyun-Taek Kim, Dong-Il Kim, June Myoung Kim, Won Do Heo, Dae-Won Kim, Chang-Yeol Yeo, Cheol-Hee Kim, Qing-song Liu |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/2dee18b6e6df45e992bdfb6659b177d0 |
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