Ruthenium(II)-enabled para-selective C–H difluoromethylation of anilides and their derivatives

Selective para-functionalization of substituted arenes is a formidable challenge in homogeneous catalysis. Here, the authors achieved the para-selective C-H difluoromethylation of anilides, indolines and tetrahydroquinolines with a ruthenium catalyst in good yields and apply it to the synthesis of b...

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Bibliographic Details
Main Authors: Chunchen Yuan, Lei Zhu, Changpeng Chen, Xiaolan Chen, Yong Yang, Yu Lan, Yingsheng Zhao
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/2e010d01252e4fb4a3b57e589263ff4a
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