R-Ras-Akt axis induces endothelial lumenogenesis and regulates the patency of regenerating vasculature

Formation of the vascular lumen initiates the blood flow and it is crucial for tissue homeostasis. Here, Li et. al show that the R-Ras-Akt signaling axis is crucial for reparative angiogenesis in mice because it stabilizes the microtubule cytoskeleton in endothelial cells to promote endothelial lume...

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Autores principales: Fangfei Li, Junko Sawada, Masanobu Komatsu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2e089150929e47c5bc3c05ddcd89b791
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