Placental extract suppresses the formation of fibrotic deposits by tumor necrosis factor alpha and transforming growth factor beta-induced epithelial–mesenchymal transition in ARPE-19 cells

Abstract Objective Epithelial–mesenchymal transition (EMT) is involved in the development of proliferative vitreoretinopathy (PVR) and subsequent fibrosis. Previously, we demonstrated that placental extract ameliorates fibrosis in a mouse model of non-alcoholic steatohepatitis. In this study, we eva...

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Détails bibliographiques
Auteurs principaux: Kyoko Igarashi, Koji Sugimoto, Eiichi Hirano
Format: article
Langue:EN
Publié: BMC 2021
Sujets:
R
Accès en ligne:https://doaj.org/article/2e295a89b4294e8c9b64001ef589ca07
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