Tumor progression locus 2 (Tpl2) deficiency does not protect against obesity-induced metabolic disease.

Tumor progression locus 2 (Tpl2) deficiency does not protect against obesity-induced metabolic disease.

Obesity is associated with a state of chronic low grade inflammation that plays an important role in the development of insulin resistance. Tumor progression locus 2 (Tpl2) is a serine/threonine mitogen activated protein kinase kinase kinase (MAP3K) involved in regulating responses to specific infla...

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Autores principales: Graeme I Lancaster, Greg M Kowalski, Emma Estevez, Michael J Kraakman, George Grigoriadis, Mark A Febbraio, Steve Gerondakis, Ashish Banerjee
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/2e31a491233e4894a1717b561203ebd5
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https://doaj.org/article/2e31a491233e4894a1717b561203ebd5

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