Tumor progression locus 2 (Tpl2) deficiency does not protect against obesity-induced metabolic disease.
Obesity is associated with a state of chronic low grade inflammation that plays an important role in the development of insulin resistance. Tumor progression locus 2 (Tpl2) is a serine/threonine mitogen activated protein kinase kinase kinase (MAP3K) involved in regulating responses to specific infla...
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Autores principales: | Graeme I Lancaster, Greg M Kowalski, Emma Estevez, Michael J Kraakman, George Grigoriadis, Mark A Febbraio, Steve Gerondakis, Ashish Banerjee |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/2e31a491233e4894a1717b561203ebd5 |
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