“Ryanopathies” and RyR2 dysfunctions: can we further decipher them using in vitro human disease models?
Abstract The regulation of intracellular calcium (Ca2+) homeostasis is fundamental to maintain normal functions in many cell types. The ryanodine receptor (RyR), the largest intracellular calcium release channel located on the sarco/endoplasmic reticulum (SR/ER), plays a key role in the intracellula...
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Autores principales: | Yvonne Sleiman, Alain Lacampagne, Albano C. Meli |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Publishing Group
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/2e323332603b40fba9c18bbfb2a854fd |
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