Insight into the stability of cross-β amyloid fibril from VEALYL short peptide with molecular dynamics simulation.

Amyloid fibrils are found in many fatal neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, type II diabetes, and prion disease. The VEALYL short peptide from insulin has been confirmed to aggregate amyloid-like fibrils. However, the aggregation mechanism of amyloi...

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Autores principales: Wei Ye, Yue Chen, Wei Wang, Qingfen Yu, Yixue Li, Jian Zhang, Hai-Feng Chen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/2e44d7e4452d4acd9b9d0c3562544a87
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