DNAM-1/CD226 is functionally expressed on acute myeloid leukemia (AML) cells and is associated with favorable prognosis

Abstract DNAM-1 is reportedly expressed on cytotoxic T and NK cells and, upon interaction with its ligands CD112 and CD155, plays an important role in tumor immunosurveillance. It has also been reported to be functionally expressed by myeloid cells, but expression and function on malignant cells of...

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Auteurs principaux: Anna Chashchina, Melanie Märklin, Clemens Hinterleitner, Helmut R. Salih, Jonas S. Heitmann, Boris Klimovich
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/2e4bb1f1327b40e887f1df34077bc07f
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