Synergistic effects of celecoxib and bupropion in a model of chronic inflammation-related depression in mice.

This study was aimed to characterize the depression-like behaviour in the classical model of chronic inflammation induced by Complete Freund's Adjuvant (CFA). Male Swiss mice received an intraplantar (i.pl.) injection of CFA (50 µl/paw) or vehicle. Behavioural and inflammatory responses were me...

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Autores principales: Izaque S Maciel, Rodrigo B M Silva, Fernanda B Morrone, João B Calixto, Maria M Campos
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/2e5bdd3473d1444d8f479d1d71d7ed70
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