COVID-19 vaccines that reduce symptoms but do not block infection need higher coverage and faster rollout to achieve population impact
Abstract Trial results for two COVID-19 vaccines suggest at least 90% efficacy against symptomatic disease (VEDIS). It remains unknown whether this efficacy is mediated by lowering SARS-CoV-2 infection susceptibility (VESUSC) or development of symptoms after infection (VESYMP). We aim to assess and...
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Main Authors: | David A. Swan, Chloe Bracis, Holly Janes, Mia Moore, Laura Matrajt, Daniel B. Reeves, Eileen Burns, Deborah Donnell, Myron S. Cohen, Joshua T. Schiffer, Dobromir Dimitrov |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/2eab7a70fea74c65a94d95d63fb05ed5 |
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