Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.

The role of different lineage specific transcription factors in directing hematopoietic cell fate towards myeloid lineage is well established but the status of epigenetic modifications has not been defined during this important developmental process. We used non proliferating, PU.1 inducible myeloid...

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Autores principales: Manjula Karpurapu, Ravi Ranjan, Jing Deng, Sangwoon Chung, Yong Gyu Lee, Lei Xiao, Teja Srinivas Nirujogi, Jeffrey R Jacobson, Gye Young Park, John W Christman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/2ed2362a0d03425598f8fb4d2394921e
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