Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.
The role of different lineage specific transcription factors in directing hematopoietic cell fate towards myeloid lineage is well established but the status of epigenetic modifications has not been defined during this important developmental process. We used non proliferating, PU.1 inducible myeloid...
Guardado en:
Autores principales: | Manjula Karpurapu, Ravi Ranjan, Jing Deng, Sangwoon Chung, Yong Gyu Lee, Lei Xiao, Teja Srinivas Nirujogi, Jeffrey R Jacobson, Gye Young Park, John W Christman |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2ed2362a0d03425598f8fb4d2394921e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The epigenetic pioneer EGR2 initiates DNA demethylation in differentiating monocytes at both stable and transient binding sites
por: Karina Mendes, et al.
Publicado: (2021) -
Multivalent nanosystems: targeting monocytes/macrophages
por: Poupot R, et al.
Publicado: (2018) -
Macrophages and Monocytes: “Trojan Horses” in COVID-19
por: Elena Percivalle, et al.
Publicado: (2021) -
Myeloid Krüppel-like factor 2 is a critical regulator of metabolic inflammation
por: David R. Sweet, et al.
Publicado: (2020) -
<italic toggle="yes">Bordetella</italic> Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells
por: Jawid Nazir Ahmad, et al.
Publicado: (2019)