Attention to time-of-day variability improves the reproducibility of gene expression patterns in multiple sclerosis

Summary: Low reproducibility in gene expression profiles has been observed in transcriptome studies, and this often limits applying findings to clinical practice. Here, we show time-of-day effects on gene expression and analytical schemes to increase the reproducibility in expression patterns. We re...

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Bibliographic Details
Main Authors: Suihong Huang, Tan Wu, Alexander Y. Lau, Cheryl Au, Hao Huang, Xin Wang, Jin Young Kim
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/2ef2ecb9cb3e4014ae75c18ba779c1e2
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