The impact of individual human cytochrome P450 enzymes on oxidative metabolism of anticancer drug lenvatinib
Lenvatinib, a small molecule tyrosine kinase inhibitor (TKI), exhibits good inhibitory effect in several types of carcinomas. Specifically, it is the most effective TKI used for treatment of thyroid cancer. To extend pharmacokinetics data on this anticancer agent, we aimed to identify the metabolite...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Elsevier
2022
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| Accès en ligne: | https://doaj.org/article/2f244a7545cb4a5faf7f44487ac55988 |
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