SV2 mediates entry of tetanus neurotoxin into central neurons.

Tetanus neurotoxin causes the disease tetanus, which is characterized by rigid paralysis. The toxin acts by inhibiting the release of neurotransmitters from inhibitory neurons in the spinal cord that innervate motor neurons and is unique among the clostridial neurotoxins due to its ability to shuttl...

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Bibliographic Details
Main Authors: Felix L Yeh, Min Dong, Jun Yao, William H Tepp, Guangyun Lin, Eric A Johnson, Edwin R Chapman
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
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Online Access:https://doaj.org/article/2f2b210be7e34fba901ff7f6cca7f8b6
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