Recurrent integration of human papillomavirus genomes at transcriptional regulatory hubs

Abstract Oncogenic human papillomavirus (HPV) genomes are often integrated into host chromosomes in HPV-associated cancers. HPV genomes are integrated either as a single copy or as tandem repeats of viral DNA interspersed with, or without, host DNA. Integration occurs frequently in common fragile si...

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Autores principales: Alix Warburton, Tovah E. Markowitz, Joshua P. Katz, James M. Pipas, Alison A. McBride
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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R
Acceso en línea:https://doaj.org/article/2f2cfc279c734d6eb70f9f70b5b5de01
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