Recurrent integration of human papillomavirus genomes at transcriptional regulatory hubs
Abstract Oncogenic human papillomavirus (HPV) genomes are often integrated into host chromosomes in HPV-associated cancers. HPV genomes are integrated either as a single copy or as tandem repeats of viral DNA interspersed with, or without, host DNA. Integration occurs frequently in common fragile si...
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Main Authors: | Alix Warburton, Tovah E. Markowitz, Joshua P. Katz, James M. Pipas, Alison A. McBride |
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Format: | article |
Language: | EN |
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Nature Portfolio
2021
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Online Access: | https://doaj.org/article/2f2cfc279c734d6eb70f9f70b5b5de01 |
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