Identification and structural analysis of the tripartite α-pore forming toxin of Aeromonas hydrophila

Pore forming toxins (PFTs) form the major group of virulence factors in many pathogenic bacteria. Here the authors identify tripartite α-helical PFTs in pathogenic Gram negative bacteria and structurally characterize AhlABC from Aeromonas hydrophila and propose a model for its pore assembly.

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Autores principales: Jason S. Wilson, Alicia M. Churchill-Angus, Simon P. Davies, Svetlana E. Sedelnikova, Svetomir B. Tzokov, John B. Rafferty, Per A. Bullough, Claudine Bisson, Patrick J. Baker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2f6b67a180744391895b4f4a9d6daa29
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