Functional and computational identification of a rescue mutation near the active site of an mRNA methyltransferase
Abstract RNA-based drugs are an emerging class of therapeutics combining the immense potential of DNA gene-therapy with the absence of genome integration-associated risks. While the synthesis of such molecules is feasible, large scale in vitro production of humanised mRNA remains a biochemical and e...
Guardado en:
Autores principales: | Pierre-Yves Colin, Paul A. Dalby |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/2f9517bf037f477d8cdc334243cc1253 |
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