RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2

RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2

RALYL is a liver progenitor cell-specific gene but its role in hepatocellular carcinoma (HCC) remains unknown. Here, the authors demonstrate that RALYL regulates HCC stemness through upregulation of TGF-β2 mRNA stability by decreasing N6-methyladenosine modification.

Guardado en:
Detalles Bibliográficos
Autores principales: Xia Wang, Jin Wang, Yu-Man Tsui, Chaoran Shi, Ying Wang, Xin Zhang, Qian Yan, Miao Chen, Chen Jiang, Yun-Fei Yuan, Chun-Ming Wong, Ming Liu, Zeng-yu Feng, Honglin Chen, Irene Oi Lin Ng, Lingxi Jiang, Xin-Yuan Guan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/2fb80e31fc6b42d4945a5ded63e83e44
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/2fb80e31fc6b42d4945a5ded63e83e44

Ejemplares similares