Synthetic liver fibrotic niche extracts achieve in vitro hepatoblasts phenotype enhancement and expansion

Summary: It is still a challenge for synthesizing ‘cellular niche-mimics’ in vitro with satisfactory reproducibility and fidelity to recreate the natural niche components (e.g., extracellular matrices and soluble factors) for stem cell cultivation. Inspired by the massive amplification of hepatic pr...

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Autores principales: Yuying Zhang, Anqi Guo, Cheng Lyu, Ran Bi, Zhaozhao Wu, Wenjing Li, Peng Zhao, Yudi Niu, Jie Na, Jianzhong Jeff Xi, Yanan Du
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/2fbacdcc82ff41d08de48209a19af3af
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