Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents

Tuberculosis (TB) remains one of the world’s deadliest communicable diseases, novel anti-TB agents are urgently needed due to severe drug resistance and the co-epidemic of TB/HIV. Here, the authors show that anti-mycobacterial ilamycin congeners bearing unusual structural units possess extremely pot...

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Autores principales: Junying Ma, Hongbo Huang, Yunchang Xie, Zhiyong Liu, Jin Zhao, Chunyan Zhang, Yanxi Jia, Yun Zhang, Hua Zhang, Tianyu Zhang, Jianhua Ju
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2fdc0cee55b14abf9e63f17c5c93ec08
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