Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation

Recording systems would allow synthetic organisms to store a ‘memory’ of a past event for future reference. Here the authors design an epigenetic memory system inE. colithat methylates DNA in response to exogenous and endogenous signals.

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Detalles Bibliográficos
Autores principales: Johannes A. H. Maier, Raphael Möhrle, Albert Jeltsch
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/2febfd6e7e484944bd24078487ec22e8
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