Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation

Recording systems would allow synthetic organisms to store a ‘memory’ of a past event for future reference. Here the authors design an epigenetic memory system inE. colithat methylates DNA in response to exogenous and endogenous signals.

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Autores principales:	Johannes A. H. Maier, Raphael Möhrle, Albert Jeltsch
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2febfd6e7e484944bd24078487ec22e8
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spelling	oai:doaj.org-article:2febfd6e7e484944bd24078487ec22e82021-12-02T17:06:28ZDesign of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation10.1038/ncomms153362041-1723https://doaj.org/article/2febfd6e7e484944bd24078487ec22e82017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15336https://doaj.org/toc/2041-1723Recording systems would allow synthetic organisms to store a ‘memory’ of a past event for future reference. Here the authors design an epigenetic memory system inE. colithat methylates DNA in response to exogenous and endogenous signals.Johannes A. H. MaierRaphael MöhrleAlbert JeltschNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Johannes A. H. Maier Raphael Möhrle Albert Jeltsch Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation
description	Recording systems would allow synthetic organisms to store a ‘memory’ of a past event for future reference. Here the authors design an epigenetic memory system inE. colithat methylates DNA in response to exogenous and endogenous signals.
format	article
author	Johannes A. H. Maier Raphael Möhrle Albert Jeltsch
author_facet	Johannes A. H. Maier Raphael Möhrle Albert Jeltsch
author_sort	Johannes A. H. Maier
title	Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation
title_short	Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation
title_full	Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation
title_fullStr	Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation
title_full_unstemmed	Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation
title_sort	design of synthetic epigenetic circuits featuring memory effects and reversible switching based on dna methylation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2febfd6e7e484944bd24078487ec22e8
work_keys_str_mv	AT johannesahmaier designofsyntheticepigeneticcircuitsfeaturingmemoryeffectsandreversibleswitchingbasedondnamethylation AT raphaelmohrle designofsyntheticepigeneticcircuitsfeaturingmemoryeffectsandreversibleswitchingbasedondnamethylation AT albertjeltsch designofsyntheticepigeneticcircuitsfeaturingmemoryeffectsandreversibleswitchingbasedondnamethylation
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Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation

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