Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation
Recording systems would allow synthetic organisms to store a ‘memory’ of a past event for future reference. Here the authors design an epigenetic memory system inE. colithat methylates DNA in response to exogenous and endogenous signals.
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Autores principales: | Johannes A. H. Maier, Raphael Möhrle, Albert Jeltsch |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/2febfd6e7e484944bd24078487ec22e8 |
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