Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly.

Non-structural protein 2 (NS2) plays an important role in hepatitis C virus (HCV) assembly, but neither the exact contribution of this protein to the assembly process nor its complete structure are known. In this study we used a combination of genetic, biochemical and structural methods to decipher...

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Autores principales: Vlastimil Jirasko, Roland Montserret, Ji Young Lee, Jérôme Gouttenoire, Darius Moradpour, Francois Penin, Ralf Bartenschlager
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/2ff4b53a56b6492dab288266050b497d
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