Engineering the geometrical shape of mesenchymal stromal cells through defined cyclic stretch regimens

Abstract Stem cells have been predicted to improve disease outcomes and patient lives. Steering stem cell fate - through controlling cell shape - may substantially accelerate progress towards this goal. As mesenchymal stromal cells (MSCs) are continuously exposed in vivo to a dynamically changing bi...

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Autores principales: Brandan Walters, Tatiana Uynuk-Ool, Miriam Rothdiener, Julian Palm, Melanie L. Hart, Jan P. Stegemann, Bernd Rolauffs
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/300e8f51c90a4d3c98cf2320425ab844
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