Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer

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Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer

Abstract The colony stimulating factor 2 receptor subunit beta (CSF2RB) is the common signaling subunit of the cytokine receptors for IL‐3, IL‐5, and GM‐CSF. Several studies have shown that spontaneous and random mutants of CSF2RB can lead to ligand independence in vitro. To date, no report(s) have...

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Détails bibliographiques
Auteurs principaux:	Mamoon Rashid, Rizwan Ali, Bader Almuzzaini, Hao Song, Alshaimaa AlHallaj, Al Abdulrahman Abdulkarim, Omar Mohamed Baz, Hajar Al Zahrani, Muhammed Mustafa Sabeena, Wardah Alharbi, Mohamed Hussein, Mohamed Boudjelal
Format:	article
Langue:	EN
Publié:	Wiley 2021
Sujets:	breast cancer breast cancer cell line CSF2RB‐activating mutation cytokine receptor hβc receptor JAK2 inhibitor Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Accès en ligne:	https://doaj.org/article/301f3883e51a43d9bf7f977108cd73df
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