Experimental Studies of the Effect of <i>Schisandrachinensis</i> Extract on the State of Adaptive Capabilities of Rats under Chronic and General Exposure to Cold

Currently, there is an objective need to create fortified food products that allow not only to provide the body with energy, but also to replenish the deficiency of essential nutrients. A generalization of the information published by Rospotrebnadzor and the Institute of Nutrition of the Russian Aca...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Irina Sergeeva, Tatyana Kiseleva, Valentina Pomozova, Nataliy Shkrabtak, Nina Frolova, Alexander Vereshchagin
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>Schisandrachinensis</i> (Turcz.) Baill cold food biologically active substances Medicine R
Acceso en línea:	https://doaj.org/article/303d0cdb8ead40639ae019c95c02e6c5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:303d0cdb8ead40639ae019c95c02e6c5
record_format	dspace
spelling	oai:doaj.org-article:303d0cdb8ead40639ae019c95c02e6c52021-11-25T17:48:18ZExperimental Studies of the Effect of <i>Schisandrachinensis</i> Extract on the State of Adaptive Capabilities of Rats under Chronic and General Exposure to Cold10.3390/ijerph1822117801660-46011661-7827https://doaj.org/article/303d0cdb8ead40639ae019c95c02e6c52021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/22/11780https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601Currently, there is an objective need to create fortified food products that allow not only to provide the body with energy, but also to replenish the deficiency of essential nutrients. A generalization of the information published by Rospotrebnadzor and the Institute of Nutrition of the Russian Academy of Medical Sciences indicates a deficiency in the diet of Russians of vitamins C, group B and β-carotene and minerals, including calcium and iron, regardless of the season of the year. The identified deviations lead to a violation of the immune status, a decrease in the body’s resistance to infections, and other unfavorable environmental factors, leading to an increase in the level of morbidity and a decrease in working capacity. The main unfavorable climatic factor that the population of the Far Eastern region has to face is low freezing temperatures. Adaptation to cold exposure is a complex process that requires a long period and may be accompanied by functional disorders and morphological changes in body tissues. In connection with the above, the problem of increasing the adaptive capabilities of a person to unfavorable environmental factors by means of correcting daily nutrition, providing the body with essential macro- and micronutrients, which is important in the prevention of possible diseases, is of particular importance. This study is aimed at assessing the effect of <i>Schisandrachinensis</i> extract on the adaptive capacity of rats in conditions of chronic and general cold. It was found that the extracts obtained from the fruits of <i>Schisandra chinensis</i> are characterized by a high content of biologically active substances. In experiments with determining the duration of running on the treadmill, a distinct act-protective effect was observed with the introduction of <i>Schisandra chinensis</i> extracts at a dose of 150 mg/day, against the background of reduced resistance to physical activity due to cold exposure. It was found that exposure to cold significantly reduced the swimming resistance of rats on all days of the study. The introduction of <i>Schisandra chinensis</i> extract into the diet led to an increase in resistance to fatigue and an increase in the duration of swimming on all days of the experiment. Conclusions: in this experimental model, a gradually increasing effect of increasing the physical performance of rats was demonstrated with prolonged (28 days) intake of the developed drinks, which coincides with the literature data on a number of other adaptogens and indicates the presence of cumulative properties of biologically active substances of Schisandra extract.Irina SergeevaTatyana KiselevaValentina PomozovaNataliy ShkrabtakNina FrolovaAlexander VereshchaginMDPI AGarticle<i>Schisandrachinensis</i> (Turcz.) Baillcoldfoodbiologically active substancesMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11780, p 11780 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	<i>Schisandrachinensis</i> (Turcz.) Baill cold food biologically active substances Medicine R
spellingShingle	<i>Schisandrachinensis</i> (Turcz.) Baill cold food biologically active substances Medicine R Irina Sergeeva Tatyana Kiseleva Valentina Pomozova Nataliy Shkrabtak Nina Frolova Alexander Vereshchagin Experimental Studies of the Effect of <i>Schisandrachinensis</i> Extract on the State of Adaptive Capabilities of Rats under Chronic and General Exposure to Cold
description	Currently, there is an objective need to create fortified food products that allow not only to provide the body with energy, but also to replenish the deficiency of essential nutrients. A generalization of the information published by Rospotrebnadzor and the Institute of Nutrition of the Russian Academy of Medical Sciences indicates a deficiency in the diet of Russians of vitamins C, group B and β-carotene and minerals, including calcium and iron, regardless of the season of the year. The identified deviations lead to a violation of the immune status, a decrease in the body’s resistance to infections, and other unfavorable environmental factors, leading to an increase in the level of morbidity and a decrease in working capacity. The main unfavorable climatic factor that the population of the Far Eastern region has to face is low freezing temperatures. Adaptation to cold exposure is a complex process that requires a long period and may be accompanied by functional disorders and morphological changes in body tissues. In connection with the above, the problem of increasing the adaptive capabilities of a person to unfavorable environmental factors by means of correcting daily nutrition, providing the body with essential macro- and micronutrients, which is important in the prevention of possible diseases, is of particular importance. This study is aimed at assessing the effect of <i>Schisandrachinensis</i> extract on the adaptive capacity of rats in conditions of chronic and general cold. It was found that the extracts obtained from the fruits of <i>Schisandra chinensis</i> are characterized by a high content of biologically active substances. In experiments with determining the duration of running on the treadmill, a distinct act-protective effect was observed with the introduction of <i>Schisandra chinensis</i> extracts at a dose of 150 mg/day, against the background of reduced resistance to physical activity due to cold exposure. It was found that exposure to cold significantly reduced the swimming resistance of rats on all days of the study. The introduction of <i>Schisandra chinensis</i> extract into the diet led to an increase in resistance to fatigue and an increase in the duration of swimming on all days of the experiment. Conclusions: in this experimental model, a gradually increasing effect of increasing the physical performance of rats was demonstrated with prolonged (28 days) intake of the developed drinks, which coincides with the literature data on a number of other adaptogens and indicates the presence of cumulative properties of biologically active substances of Schisandra extract.
format	article
author	Irina Sergeeva Tatyana Kiseleva Valentina Pomozova Nataliy Shkrabtak Nina Frolova Alexander Vereshchagin
author_facet	Irina Sergeeva Tatyana Kiseleva Valentina Pomozova Nataliy Shkrabtak Nina Frolova Alexander Vereshchagin
author_sort	Irina Sergeeva
title	Experimental Studies of the Effect of <i>Schisandrachinensis</i> Extract on the State of Adaptive Capabilities of Rats under Chronic and General Exposure to Cold
title_short	Experimental Studies of the Effect of <i>Schisandrachinensis</i> Extract on the State of Adaptive Capabilities of Rats under Chronic and General Exposure to Cold
title_full	Experimental Studies of the Effect of <i>Schisandrachinensis</i> Extract on the State of Adaptive Capabilities of Rats under Chronic and General Exposure to Cold
title_fullStr	Experimental Studies of the Effect of <i>Schisandrachinensis</i> Extract on the State of Adaptive Capabilities of Rats under Chronic and General Exposure to Cold
title_full_unstemmed	Experimental Studies of the Effect of <i>Schisandrachinensis</i> Extract on the State of Adaptive Capabilities of Rats under Chronic and General Exposure to Cold
title_sort	experimental studies of the effect of <i>schisandrachinensis</i> extract on the state of adaptive capabilities of rats under chronic and general exposure to cold
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/303d0cdb8ead40639ae019c95c02e6c5
work_keys_str_mv	AT irinasergeeva experimentalstudiesoftheeffectofischisandrachinensisiextractonthestateofadaptivecapabilitiesofratsunderchronicandgeneralexposuretocold AT tatyanakiseleva experimentalstudiesoftheeffectofischisandrachinensisiextractonthestateofadaptivecapabilitiesofratsunderchronicandgeneralexposuretocold AT valentinapomozova experimentalstudiesoftheeffectofischisandrachinensisiextractonthestateofadaptivecapabilitiesofratsunderchronicandgeneralexposuretocold AT nataliyshkrabtak experimentalstudiesoftheeffectofischisandrachinensisiextractonthestateofadaptivecapabilitiesofratsunderchronicandgeneralexposuretocold AT ninafrolova experimentalstudiesoftheeffectofischisandrachinensisiextractonthestateofadaptivecapabilitiesofratsunderchronicandgeneralexposuretocold AT alexandervereshchagin experimentalstudiesoftheeffectofischisandrachinensisiextractonthestateofadaptivecapabilitiesofratsunderchronicandgeneralexposuretocold
_version_	1718411975773388800

Experimental Studies of the Effect of <i>Schisandrachinensis</i> Extract on the State of Adaptive Capabilities of Rats under Chronic and General Exposure to Cold

Ejemplares similares