Establishing a yeast-based screening system for discovery of human GLUT5 inhibitors and activators
Abstract Human GLUT5 is a fructose-specific transporter in the glucose transporter family (GLUT, SLC2 gene family). Its substrate-specificity and tissue-specific expression make it a promising target for treatment of diabetes, metabolic syndrome and cancer, but few GLUT5 inhibitors are known. To ide...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/304ac976992841c9828f6fc9c777528f |
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