PMS1077 sensitizes TNF-α induced apoptosis in human prostate cancer cells by blocking NF-κB signaling pathway.
Our previous studies have demonstrated that PMS1077, a platelet-activating factor (PAF) antagonist, could induce apoptosis of Raji cells. However, the mechanism of action has not yet been determined. The nuclear transcription factor-kappa B (NF-κB) signaling pathway plays a critical role in tumor ce...
Guardado en:
Autores principales: | Jie Shi, Jing Chen, Nawal Serradji, Ximing Xu, Heng Zhou, Yinxing Ma, Zhihong Sun, Peng Jiang, Yuping Du, Jinbo Yang, Changzhi Dong, Qin Wang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/306cbc1f5ff04cafa91aa34ffbe4b048 |
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