Chromatin fibers stabilize nucleosomes under torsional stress

Torsional stress is generated during DNA replication and transcription, however, the propagation of twist in condensed chromatin is poorly understood. Here the authors measure how force and torque impact chromatin fibers and find that the fibers fold into a left-handed superhelix that can be stabili...

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Auteurs principaux: Artur Kaczmarczyk, He Meng, Orkide Ordu, John van Noort, Nynke H. Dekker
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/30a70ffb95644882808b1311d671a36e
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