Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures

During translocation by viral RNA-dependent RNA polymerases (RdRP), the template-product RNA duplex moves in an asymmetric manner. Here the authors describe several crystal structures of RdRP translocations intermediates that, along with enzymological data, provide a comprehensive view of RdRP trans...

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Autores principales: Meihua Wang, Rui Li, Bo Shu, Xuping Jing, Han-Qing Ye, Peng Gong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/30bdaf61e4394908a7fdee800bf4c089
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