In vivo nuclear capture and molecular profiling identifies Gmeb1 as a transcriptional regulator essential for dopamine neuron function

Despite the known role of midbrain dopaminergic (mDA) signaling in the homeostatic control of mood and motor functions, little is known about how gene expression in these neurons is regulated. Here, authors develop an in vivo nuclear tagging and capture technique for low-input chromatin accessibilit...

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Autores principales: Luis M. Tuesta, Mohamed N. Djekidel, Renchao Chen, Falong Lu, Wengang Wang, Bernardo L. Sabatini, Yi Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/30e693ae83634bd09940961f8cef6c42
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