Detecting clusters of mutations.

Positive selection for protein function can lead to multiple mutations within a small stretch of DNA, i.e., to a cluster of mutations. Recently, Wagner proposed a method to detect such mutation clusters. His method, however, did not take into account that residues with high solvent accessibility are...

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Autores principales: Tong Zhou, Peter J Enyeart, Claus O Wilke
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/30ee153206db49ecbf9e29b851503ea5
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