Detecting clusters of mutations.
Positive selection for protein function can lead to multiple mutations within a small stretch of DNA, i.e., to a cluster of mutations. Recently, Wagner proposed a method to detect such mutation clusters. His method, however, did not take into account that residues with high solvent accessibility are...
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Main Authors: | Tong Zhou, Peter J Enyeart, Claus O Wilke |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2008
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Online Access: | https://doaj.org/article/30ee153206db49ecbf9e29b851503ea5 |
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