A unified resource and configurable model of the synapse proteome and its role in disease

Abstract Genes encoding synaptic proteins are highly associated with neuronal disorders many of which show clinical co-morbidity. We integrated 58 published synaptic proteomic datasets that describe over 8000 proteins and combined them with direct protein–protein interactions and functional metadata...

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Autores principales: Oksana Sorokina, Colin Mclean, Mike D. R. Croning, Katharina F. Heil, Emilia Wysocka, Xin He, David Sterratt, Seth G. N. Grant, Thomas I. Simpson, J. Douglas Armstrong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3100788543c544378e78f9e3f69c92a7
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