Proteasomal degradation of TRIM5alpha during retrovirus restriction.
The host protein TRIM5alpha inhibits retroviral infection at an early post-penetration stage by targeting the incoming viral capsid. While the detailed mechanism of restriction remains unclear, recent studies have implicated the activity of cellular proteasomes in the restriction of retroviral rever...
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| Main Authors: | , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2008
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| Subjects: | |
| Online Access: | https://doaj.org/article/311c936a68f9460e884217fee707e3a9 |
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