Interplay of Trypanosome Lytic Factor and innate immune cells in the resolution of cutaneous Leishmania infection.

Trypanosome Lytic Factor (TLF) is a primate-specific high-density lipoprotein (HDL) complex that, through the cation channel-forming protein apolipoprotein L-1 (APOL1), provides innate immunity to select kinetoplastid parasites. The immunoprotective effects of TLF have been extensively investigated...

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Bibliographic Details
Main Authors: Jyoti Pant, Marie Samanovic, Maria T Nelson, Mert K Keceli, Joseph Verdi, Stephen M Beverley, Jayne Raper
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/3122d2551537448dafd74d30109fbcd5
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