A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

SWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional activation of GAS6 and a set of SWI/SNF target genes.

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Autores principales: Elena Grossi, Ivan Raimondi, Enrique Goñi, Jovanna González, Francesco P. Marchese, Vicente Chapaprieta, José I. Martín-Subero, Shuling Guo, Maite Huarte
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/312881ea5ccf4917ac2bc11fe60be750
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