A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

SWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional activation of GAS6 and a set of SWI/SNF target genes.

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Autores principales: Elena Grossi, Ivan Raimondi, Enrique Goñi, Jovanna González, Francesco P. Marchese, Vicente Chapaprieta, José I. Martín-Subero, Shuling Guo, Maite Huarte
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/312881ea5ccf4917ac2bc11fe60be750
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spelling oai:doaj.org-article:312881ea5ccf4917ac2bc11fe60be7502021-12-02T15:39:09ZA lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions10.1038/s41467-020-14623-32041-1723https://doaj.org/article/312881ea5ccf4917ac2bc11fe60be7502020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14623-3https://doaj.org/toc/2041-1723SWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional activation of GAS6 and a set of SWI/SNF target genes.Elena GrossiIvan RaimondiEnrique GoñiJovanna GonzálezFrancesco P. MarcheseVicente ChapaprietaJosé I. Martín-SuberoShuling GuoMaite HuarteNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Elena Grossi
Ivan Raimondi
Enrique Goñi
Jovanna González
Francesco P. Marchese
Vicente Chapaprieta
José I. Martín-Subero
Shuling Guo
Maite Huarte
A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
description SWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional activation of GAS6 and a set of SWI/SNF target genes.
format article
author Elena Grossi
Ivan Raimondi
Enrique Goñi
Jovanna González
Francesco P. Marchese
Vicente Chapaprieta
José I. Martín-Subero
Shuling Guo
Maite Huarte
author_facet Elena Grossi
Ivan Raimondi
Enrique Goñi
Jovanna González
Francesco P. Marchese
Vicente Chapaprieta
José I. Martín-Subero
Shuling Guo
Maite Huarte
author_sort Elena Grossi
title A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
title_short A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
title_full A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
title_fullStr A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
title_full_unstemmed A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
title_sort lncrna-swi/snf complex crosstalk controls transcriptional activation at specific promoter regions
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/312881ea5ccf4917ac2bc11fe60be750
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