PPAR agonist-induced reduction of Mcp1 in atherosclerotic plaques of obese, insulin-resistant mice depends on adiponectin-induced Irak3 expression.

Synthetic peroxisome proliferator-activated receptor (PPAR) agonists are used to treat dyslipidemia and insulin resistance. In this study, we examined molecular mechanisms that explain differential effects of a PPARα agonist (fenofibrate) and a PPARγ agonist (rosiglitazone) on macrophages during obe...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Maarten Hulsmans, Benjamine Geeraert, Thierry Arnould, Christos Tsatsanis, Paul Holvoet
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/315a684639b74a6084a423564836f22e
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!