Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity

Qiang Huang et al. fed C. elegans with E. coli containing phosphorothioate (PT) DNA or a control strain and evaluated the impact on animal physiology. They observed that worms fed PT( + ) diets exhibited low reactive oxygen species, more active movement, and a longer lifespan compared to controls, s...

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Autores principales:	Qiang Huang, Ruohan Li, Tao Yi, Fengsong Cong, Dayong Wang, Zixin Deng, Yi-Lei Zhao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/318640d16b8842a0811fae4b39c9b4d1
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spelling	oai:doaj.org-article:318640d16b8842a0811fae4b39c9b4d12021-11-28T12:10:28ZPhosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity10.1038/s42003-021-02863-y2399-3642https://doaj.org/article/318640d16b8842a0811fae4b39c9b4d12021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02863-yhttps://doaj.org/toc/2399-3642Qiang Huang et al. fed C. elegans with E. coli containing phosphorothioate (PT) DNA or a control strain and evaluated the impact on animal physiology. They observed that worms fed PT( + ) diets exhibited low reactive oxygen species, more active movement, and a longer lifespan compared to controls, suggesting that PT-DNA may have a positive effect on animal health.Qiang HuangRuohan LiTao YiFengsong CongDayong WangZixin DengYi-Lei ZhaoNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Qiang Huang Ruohan Li Tao Yi Fengsong Cong Dayong Wang Zixin Deng Yi-Lei Zhao Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity
description	Qiang Huang et al. fed C. elegans with E. coli containing phosphorothioate (PT) DNA or a control strain and evaluated the impact on animal physiology. They observed that worms fed PT( + ) diets exhibited low reactive oxygen species, more active movement, and a longer lifespan compared to controls, suggesting that PT-DNA may have a positive effect on animal health.
format	article
author	Qiang Huang Ruohan Li Tao Yi Fengsong Cong Dayong Wang Zixin Deng Yi-Lei Zhao
author_facet	Qiang Huang Ruohan Li Tao Yi Fengsong Cong Dayong Wang Zixin Deng Yi-Lei Zhao
author_sort	Qiang Huang
title	Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity
title_short	Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity
title_full	Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity
title_fullStr	Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity
title_full_unstemmed	Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity
title_sort	phosphorothioate-dna bacterial diet reduces the ros levels in c. elegans while improving locomotion and longevity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/318640d16b8842a0811fae4b39c9b4d1
work_keys_str_mv	AT qianghuang phosphorothioatednabacterialdietreducestheroslevelsinceleganswhileimprovinglocomotionandlongevity AT ruohanli phosphorothioatednabacterialdietreducestheroslevelsinceleganswhileimprovinglocomotionandlongevity AT taoyi phosphorothioatednabacterialdietreducestheroslevelsinceleganswhileimprovinglocomotionandlongevity AT fengsongcong phosphorothioatednabacterialdietreducestheroslevelsinceleganswhileimprovinglocomotionandlongevity AT dayongwang phosphorothioatednabacterialdietreducestheroslevelsinceleganswhileimprovinglocomotionandlongevity AT zixindeng phosphorothioatednabacterialdietreducestheroslevelsinceleganswhileimprovinglocomotionandlongevity AT yileizhao phosphorothioatednabacterialdietreducestheroslevelsinceleganswhileimprovinglocomotionandlongevity
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Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity

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