The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation.
<h4>Background</h4>The regulatory subunit (R) of cAMP-dependent protein kinase (PKA) is a modular flexible protein that responds with large conformational changes to the binding of the effector cAMP. Considering its highly dynamic nature, the protein is rather stable. We studied the ther...
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| Auteurs principaux: | , , , , , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2011
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| Accès en ligne: | https://doaj.org/article/31c7d72bd67e4781abe6317a5e2de01e |
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