Directed evolution of rRNA improves translation kinetics and recombinant protein yield
Ribosome kinetics are rate-limiting for protein synthesis. Here the authors evolve diverse 16S rRNAs for enhanced protein synthesis rates and genetic code expansion efficiencies in vivo.
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Autores principales: | Fan Liu, Siniša Bratulić, Alan Costello, Teemu P. Miettinen, Ahmed H. Badran |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/32003b95f3524e2ca3a03d553664173a |
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